When I first start my eclipse after Windows 8 install, I got error:

Locking is not possible in the directory “\Eclipse\configuration\org.eclipse.osgi”.
A common reason is that the file system or Runtime Environment does not support file locking for that location.
Please choose a different location, or disable file locking passing “-Dosgi.locking=none” as a VM argument.

\Eclipse\configuration\org.eclipse.osgi\.manager\.fileTableLock

If you search on Google, it might lead you to this post but I can’t solve the issue as soon as I get into the post but I would understand the issue because of permission on the locking file “.fileTableLock” so I apply my correction on change permission setting on the file:

• Go to directory: \Eclipse-JEE-Indigo\configuration\org.eclipse.osgi\.manager
• Right click on file: .fileTableLock > Properties
• On Security Tab, Edit (permission)
• Assign Permission on group: Users for full control on this file
• Click OK and start the eclipse again.
• It’s working now.

Does it work for you?